The Law Firm of Afe Babalola & Co was founded in 1965 by Mr. Afe Babalola (as he then was) after two years of eventful pupilage with the Law firm of Ayoola & Ayoola & Co. The firm which began as a one-man chambers in 1965 is today one of the largest in Nigeria with over thirty lawyers including two Senior Advocates of Nigeria. (S.A.N.) The firm's Head Office is in Ibadan city and it presently maintains three branch offices in the cities of Lagos, Abuja and Port Harcourt and two other correspondence offices in city of Ado-Ekiti and the city of London in the United Kingdom

In 1986 the firm's main office was moved from a rented apartment to a modern four storey building at No.80, Fajuyi Road, Ekotedo, Ibadan designed and built purposely by the founder for legal practice. This building presently hosts the firm’s head office. In 2005, the firm hosted its internet website which is purely for informational purposes and in line with modern information technological developments.